Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304200 | 0.86 | MAPT (0.59) | RXFP1LMNATHRBMEN1KMT2A | |
| SCHEMBL8308248 | 0.84 | RXFP1 (0.75) | RXFP1LMNATHRBMEN1KMT2A | |
| SCHEMBL8306889 | 0.81 | RXFP1 (0.58) | RXFP1LMNATHRBMEN1KMT2A | |
| SCHEMBL8308066 | 0.76 | LMNA (0.86) | RXFP1LMNATHRBMEN1KMT2A | |
| SCHEMBL8304067 | 0.75 | LMNA (0.78) | RXFP1LMNATHRBMEN1KMT2A | |
| SCHEMBL8305881 | 0.74 | GAA (0.67) | RXFP1LMNAGAAPOLBMAPT | |
| SCHEMBL8305679 | 0.72 | RXFP1 (0.71) | RXFP1LMNATHRBKMT2APOLB | |
| SCHEMBL16639785 | 0.72 | GAA (0.55) | THRBMEN1KMT2AGAAMAPT | |
| SCHEMBL13253404 | 0.70 | KDM4E (0.62) | RXFP1LMNAMEN1KMT2APOLB | |
| SCHEMBL18997900 | 0.70 | MAPT (0.67) | RXFP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |