Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851706 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2RAB9ANPC1CA2 | |
| SCHEMBL8304295 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2RAB9ANPC1CA2 | |
| SCHEMBL8304507 | 0.77 | KMT2A (0.49) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL7968273 | 0.74 | KMT2A (0.57) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL146922 | 0.70 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL15819998 | 0.69 | HSD17B10 (0.46) | ALDH1A1SMN1; SMN2HTTTDP1KMT2A | |
| Water SCHEMBL27718168 | 0.69 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL15794568 | 0.69 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL1636840 | 0.69 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR | |
| SCHEMBL10968439 | 0.68 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2HTTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |