Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 6/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847047 | 0.81 | APP (0.36) | KMT2AMEN1 | |
| SCHEMBL3851706 | 0.81 | SMN1; SMN2 (0.43) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL8304295 | 0.81 | SMN1; SMN2 (0.43) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL8308552 | 0.77 | ALDH1A1 (0.50) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30528453 | 0.75 | MEN1 (0.44) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL22048013 | 0.74 | KMT2A (0.65) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL5946297 | 0.73 | MEN1 (0.51) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL28652940 | 0.73 | SMN1; SMN2 (0.52) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL29405880 | 0.73 | SMN1; SMN2 (0.52) | KMT2AMEN1LMNAPOLBHSD17B10 | |
| SCHEMBL9533470 | 0.72 | KMT2A (0.77) | KMT2AMEN1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538215-B1 | PROCESSES FOR PRODUCING LACTONE | TAKASAGO PERFUMERY CO LTD (JP) | 2014-11-12 | — | — | EP | disclosed |
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| CN-1031619-C | Oxazolidinone derivatives for the production of medicaments | EISAI CO LTD (JP) | 1996-04-24 | — | — | CN | disclosed |
| CN-1113240-A | Oxazolidone derivative | EISAI CO LTD (JP) | 1995-12-13 | — | — | CN | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |
| CN-1071665-A | Oxazolidinone Derivatives | EISAI CO LTD (JP) | 1993-05-05 | — | — | CN | disclosed |