Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851706 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL3847047 | 0.84 | APP (0.36) | MEN1KMT2AMAPTAPP | |
| SCHEMBL8308552 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8304507 | 0.81 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2AGAAKDM4E | |
| SCHEMBL22201585 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8303658 | 0.73 | GRM2 (0.37) | — | |
| SCHEMBL10761387 | 0.72 | MAPT (0.42) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL31703846 | 0.68 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10358336 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL617735 | 0.65 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538215-B1 | PROCESSES FOR PRODUCING LACTONE | TAKASAGO PERFUMERY CO LTD (JP) | 2014-11-12 | — | — | EP | disclosed |
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |