Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787467 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10087948 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7058356 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7120130 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL8311343 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL27625425 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL6898926 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL11690664 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SOAT1LMNAHSD17B10KDM4E | |
| SCHEMBL11690671 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SOAT1LMNAHSD17B10KDM4E | |
| SCHEMBL13104609 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SOAT1SMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912547-A2 | NEW SUBSTITUTED PYRIDYL KETO ENOLS | BAYER AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043275-A2 | NEW SUBSTITUTED PYRIDYL KETO ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-20 | — | — | WO | disclosed |