Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628878 | 0.83 | ALDH1A1 (0.43) | ALDH1A1OPRM1SOAT1KDM4EKMT2A | |
| SCHEMBL3844048 | 0.80 | KDM4E (0.38) | OPRM1KDM4EKMT2A | |
| SCHEMBL8308690 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SOAT1KDM4EKMT2AALOX15 | |
| SCHEMBL7120130 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SOAT1KMT2AALOX15MAPT | |
| SCHEMBL27847843 | 0.76 | ALDH1A1 (0.40) | ALDH1A1OPRM1KDM4EKMT2ALMNA | |
| SCHEMBL8487791 | 0.75 | KDM4E (0.36) | OPRM1KDM4EKMT2AALOX15 | |
| SCHEMBL1282033 | 0.74 | OPRM1 (0.53) | ALDH1A1OPRM1KDM4EKMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL28777414 | 0.74 | KDM4E (0.35) | OPRM1KDM4EKMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL17535049 | 0.73 | OPRM1 (0.51) | ALDH1A1OPRM1KDM4EKMT2AALOX15 | |
| Methane SCHEMBL27442652 | 0.73 | OPRM1 (0.51) | ALDH1A1OPRM1KDM4EKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |