Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794716 | 0.85 | MAPT (0.38) | AKR1B1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27328716 | 0.84 | CA1 (0.38) | AKR1B1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27316930 | 0.84 | PRSS1 (0.40) | AKR1B1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8315687 | 0.83 | AKR1B1 (0.41) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8311414 | 0.83 | AKR1B1 (0.39) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8795162 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6270429 | 0.82 | AKR1B1 (0.40) | AKR1B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8794948 | 0.82 | ALDH1A1 (0.40) | AKR1B1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8796400 | 0.82 | ALDH1A1 (0.38) | AKR1B1ALDH1A1POLBTDP1CYP3A4 | |
| SCHEMBL8794145 | 0.81 | TP53 (0.38) | AKR1B1ALDH1A1KMT2AMAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |