Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271007 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2GSK3BCACNA1CCACNA1FCACNA1D | |
| Hydrochloric Acid SCHEMBL8796125 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2GSK3BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL8308734 | 0.82 | AKR1B1 (0.43) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL8794987 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2GSK3BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL8794980 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2GSK3BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL8794145 | 0.80 | TP53 (0.38) | MAPTALDH1A1KMT2AARCYP1A2 | |
| SCHEMBL8794716 | 0.79 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9566816 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AARHIF1A | |
| SCHEMBL27328716 | 0.78 | CA1 (0.38) | MAPTALDH1A1KMT2AARMEN1 | |
| SCHEMBL27316930 | 0.78 | PRSS1 (0.40) | MAPTALDH1A1KMT2AARHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |