SCHEMBL8308735

SCHEMBL8308735

Cc1ncc(-n2nn[nH]c2=O)n1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8307690 0.71 COMT (0.36)
SCHEMBL8307323 0.71 PRMT5 (0.32) PRMT5WDR77
SCHEMBL8306697 0.70 SMN1; SMN2 (0.33)
SCHEMBL8303879 0.68
SCHEMBL8308197 0.68 ALDH1A1 (0.37)
SCHEMBL8309249 0.67 CYP3A4 (0.33)
SCHEMBL8307507 0.67 PRMT5 (0.33) PRMT5WDR77
SCHEMBL8303651 0.67 CYP1A2 (0.33) PRMT5WDR77
SCHEMBL8308731 0.67 CYP3A4 (0.36)
SCHEMBL8599564 0.65 HSP90AA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed