Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946058 | 0.84 | NOTUM (0.42) | POLBNOTUMALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5905967 | 0.82 | CYP1A2 (0.48) | HSP90AA1POLBLMNAALDH1A1CYP1A2 | |
| SCHEMBL5906191 | 0.81 | ALDH1A1 (0.42) | HSP90AA1LMNANOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL8977207 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1NPSR1MEN1MAPT | |
| SCHEMBL5906130 | 0.78 | NPSR1 (0.35) | NOTUMNPSR1 | |
| SCHEMBL5905873 | 0.77 | CYP1A2 (0.42) | POLBLMNAALDH1A1CYP2C9MEN1 | |
| SCHEMBL8977221 | 0.77 | SMN1; SMN2 (0.47) | LMNAHCAR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8686281 | 0.76 | KDM4E (0.30) | LMNAALDH1A1 | |
| SCHEMBL14347496 | 0.75 | TP53 (0.39) | POLBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17946008 | 0.74 | CYP2C9 (0.40) | POLBCYP2C9CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0708097-A1 | Herbicidally active tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1996-04-24 | — | — | EP | disclosed |