Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2160440 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL2770672 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL30280812 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL337418 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL3543973 | 0.76 | MEN1 (0.45) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL8263558 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL3787646 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL8179660 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL7311960 | 0.75 | SMN1; SMN2 (0.50) | KMT2AMEN1HTT | |
| SCHEMBL31045711 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380131-A | Heteroaryl compounds as 5-ht4 receptor ligands | SUVEN LIFE SCIENCES LTD | 2013-10-30 | — | — | CN | disclosed |
| CN-101252929-A | G protein-coupled receptor agonists | PROSIDION LTD (GB) | 2008-08-27 | — | — | CN | disclosed |
| EP-0925299-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998003507-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |