Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.68 |
| ▸ | MGLL | Q99685 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517206 | 0.88 | MAPT (0.56) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL23928536 | 0.85 | FAAH (0.70) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL23928652 | 0.82 | FAAH (0.54) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL23928604 | 0.82 | GAA (0.60) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL23928617 | 0.81 | FAAH (0.52) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL23928537 | 0.81 | MAPT (0.67) | FAAHMGLLGAARAB9AMAPT | |
| SCHEMBL3273659 | 0.81 | GAA (0.69) | GAARAB9AMAPTNPC1POLB | |
| SCHEMBL4413307 | 0.81 | GAA (0.69) | GAARAB9AMAPTNPC1POLB | |
| SCHEMBL13345208 | 0.81 | GAA (0.69) | GAARAB9AMAPTNPC1POLB | |
| SCHEMBL23928577 | 0.80 | GAA (0.53) | FAAHMGLLGAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915848-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | disclosed |
| US-5723485-A | ANALGESIC, ANTIINFLAMMATORY AGENTS | LABORATORIES UPSA (FR) | 1998-03-03 | — | — | US | disclosed |
| WO-1998005639-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |