Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13345208 | 1.00 | GAA (0.69) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL3273659 | 1.00 | GAA (0.69) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL11325422 | 0.88 | MEN1 (0.61) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL28874997 | 0.88 | MEN1 (0.57) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL11325414 | 0.88 | MAPT (0.60) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL11726036 | 0.88 | MEN1 (0.57) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL15187708 | 0.88 | RAB9A (0.57) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL23392561 | 0.87 | MEN1 (0.64) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL10403469 | 0.87 | MEN1 (0.64) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL22160190 | 0.87 | ALDH1A1 (0.71) | GAAKMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999720-B2 | Pyrazolylacylpyrazoline compounds and method for treating pain | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-06-04 | — | — | US | disclosed |
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| US-20210155609-A1 | PYRAZOLYLACYLPYRAZOLINE COMPOUNDS AND METHOD FOR TREATING PAIN | THE TRUSTEES OF INDIANA UNIVERSITY | 2021-05-27 | — | — | US | disclosed |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | DARTMOUTH COLLEGE (US) | 2019-08-22 | — | — | US | disclosed |
| US-8188080-B2 | VHR protein tyrosine phosphatase inhibitors, compositions and methods of use | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090105254-A1 | VHR PROTEIN TYROSINE PHOSPHATASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155609-A1 | PYRAZOLYLACYLPYRAZOLINE COMPOUNDS AND METHOD FOR TREATING PAIN | ACHE, TRPV1, GRIK3 | GAA 1154/4885KMT2A 3198/4885MEN1 4046/4885 |
| US-20090105254-A1 | VHR PROTEIN TYROSINE PHOSPHATASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | PTPRR, PTPRS, PTPRCAP | GAA 1857/4885KMT2A 2032/4885MEN1 4459/4885 |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | CRYZ, PIN1, PPOX | GAA 4201/4885KMT2A 792/4885MEN1 2778/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | GAA 4201/4885KMT2A 792/4885MEN1 2778/4885 |
| US-11999720-B2 | Pyrazolylacylpyrazoline compounds and method for treating pain | ACHE, TRPV1, GRIK3 | GAA 1154/4885KMT2A 3198/4885MEN1 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.