Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 9/20 | 0.42 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100648 | 0.84 | PYGB (0.43) | PYGBPYGLPYGMOGA | |
| SCHEMBL547472 | 0.84 | PYGB (0.43) | PYGBPYGLPYGMOGA | |
| SCHEMBL4879608 | 0.84 | PYGB (0.43) | PYGBPYGLPYGMOGA | |
| SCHEMBL1524726 | 0.84 | PYGB (0.43) | PYGBPYGLPYGMOGA | |
| SCHEMBL4167814 | 0.84 | PYGB (0.43) | PYGBPYGLPYGMOGA | |
| SCHEMBL9679221 | 0.80 | PYGB (0.43) | PYGBPYGLPYGM | |
| SCHEMBL9566957 | 0.80 | PYGB (0.43) | PYGBPYGLPYGM | |
| SCHEMBL9678173 | 0.80 | PYGB (0.43) | PYGBPYGLPYGM | |
| SCHEMBL15104602 | 0.80 | PYGB (0.38) | PYGBPYGLPYGMOGA | |
| SCHEMBL4853031 | 0.80 | PYGB (0.38) | PYGBPYGLPYGMOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929545-A1 | TRICYCLIC INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011093-A1 | TRICYCLIC INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-03-19 | — | — | WO | disclosed |