Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 9/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.38 |
| ▸ | PYGM | P11217 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679221 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL9678173 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL27493886 | 0.95 | PYGB (0.38) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL6382489 | 0.95 | PYGB (0.38) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL28493519 | 0.84 | PYGB (0.44) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL27827718 | 0.83 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL27827742 | 0.83 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL8308792 | 0.80 | PYGB (0.42) | PYGBPYGLPYGM | |
| SCHEMBL11216307 | 0.77 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A | |
| SCHEMBL26979603 | 0.77 | PYGB (0.43) | PYGBPYGLPYGMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431008-A4 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | — | 1992-03-11 | — | — | EP | claimed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | claimed |
| EP-0431008-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1991-06-12 | — | — | EP | claimed |
| WO-1990001931-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1990-03-08 | — | — | WO | claimed |
| EP-0532026-A2 | Oligosaccharide aromatic glycoside sulfate | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1993-03-17 | — | — | EP | disclosed |