Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.56 |
| ▸ | CA1 | P00915 | 7/20 | 0.53 |
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | APOB | P04114 | 2/20 | 0.49 |
| ▸ | MTTP | P55157 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958397 | 0.77 | MAPT (0.43) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL27033455 | 0.77 | MAPT (0.43) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL30267146 | 0.76 | EPHX2 (0.50) | CA1CA2APOBMTTPCA12 | |
| SCHEMBL31324550 | 0.76 | EPHX2 (0.50) | CA1CA2APOBMTTPCA12 | |
| SCHEMBL30748079 | 0.76 | EPHX2 (0.50) | CA1CA2APOBMTTPCA12 | |
| SCHEMBL28926914 | 0.76 | EPHX2 (0.50) | CA1CA2APOBMTTPCA12 | |
| SCHEMBL5677299 | 0.76 | CA1 (0.64) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL9136687 | 0.76 | CA1 (0.64) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL5722246 | 0.76 | CA1 (0.64) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL9368888 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579059-B1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |