Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033455 | 1.00 | MAPT (0.43) | MAPTMTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL29174247 | 0.95 | CYP1A2 (0.40) | MAPTMTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL24214577 | 0.94 | FAAH (0.43) | MAPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4016019 | 0.88 | KMT2A (0.47) | MAPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL346094 | 0.87 | CA1 (0.53) | MAPTMTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL346328 | 0.86 | ADRB3 (0.46) | HSD17B3FAAHADRB3 | |
| SCHEMBL344558 | 0.84 | MEN1 (0.40) | MAPTMTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL25554148 | 0.84 | MTNR1A (0.44) | MAPTMTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL346480 | 0.83 | FAAH (0.51) | HSD17B3FAAHADRB3 | |
| SCHEMBL29174245 | 0.83 | MTNR1A (0.34) | MAPTMTNR1AMTNR1BKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308228-A1 | PLASMA KALLIKREIN INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022197756-A1 | PLASMA KALLIKREIN INHIBITORS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |