Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574674 | 0.84 | GAA (0.65) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL11546523 | 0.78 | GAA (0.65) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL2546236 | 0.76 | GAA (0.68) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL3994806 | 0.75 | GAA (0.61) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL8309863 | 0.74 | GAA (0.60) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL14833516 | 0.72 | BRAF (0.58) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL10570828 | 0.72 | GAA (0.55) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL2743087 | 0.72 | GAA (0.61) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL12100341 | 0.72 | KDM4E (0.60) | GAAMAPTALDH1A1LMNAHPGD | |
| SCHEMBL3615656 | 0.72 | GAA (0.61) | GAAMAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745684-B1 | Method of quantitative determination of peroxides, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO LTD (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5801008-A | Method of quantitative determination of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO., LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0745684-A1 | Method of quantitative determination of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO., LTD. (JP) | 1996-12-04 | — | — | EP | disclosed |