⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552504 | 0.79 | — | — | |
| SCHEMBL7854411 | 0.73 | — | — | |
| SCHEMBL7655915 | 0.73 | — | — | |
| SCHEMBL15403707 | 0.73 | — | — | |
| SCHEMBL23280314 | 0.72 | — | — | |
| SCHEMBL967155 | 0.72 | — | — | |
| SCHEMBL967153 | 0.72 | — | — | |
| SCHEMBL45365 | 0.71 | — | — | |
| SCHEMBL21386233 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL15402893 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717738-B1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |