⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789669 | 0.73 | — | — | |
| SCHEMBL7858245 | 0.73 | — | — | |
| SCHEMBL8309034 | 0.72 | — | — | |
| SCHEMBL967155 | 0.72 | — | — | |
| SCHEMBL23280314 | 0.72 | — | — | |
| SCHEMBL1145212 | 0.72 | — | — | |
| SCHEMBL1145210 | 0.72 | — | — | |
| SCHEMBL16399339 | 0.71 | — | — | |
| SCHEMBL21386233 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL22114238 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11947073-B2 | Cast-moldable, high refractive index, rigid, gas permeable polymer formulations for an accommodating contact lens | TWENTY TWENTY THERAPEUTICS LLC (US) | 2024-04-02 | — | — | US | disclosed |
| CN-109891270-B | Castable, high refractive index, rigid, gas permeable polymeric formulations for accommodating contact lenses | 威里利生命科学有限责任公司 | 2022-08-16 | — | — | CN | disclosed |
| US-11035983-B2 | Cast-moldable, high refractive index, rigid, gas permeable polymer formulations for an accommodating contact lens | VERILY LIFE SCIENCES LLC (US) | 2021-06-15 | — | — | US | disclosed |
| US-11008413-B1 | Biocompatible materials for underlid device fabrication | VERILY LIFE SCIENCES LLC (US) | 2021-05-18 | — | — | US | disclosed |
| EP-3516432-B1 | CAST-MOLDABLE, HIGH REFRACTIVE INDEX, RIGID, GAS PERMEABLE POLYMER FORMULATIONS FOR AN ACCOMMODATING CONTACT LENS | VERILY LIFE SCIENCES LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3516432-A1 | CAST-MOLDABLE, HIGH REFRACTIVE INDEX, RIGID, GAS PERMEABLE POLYMER FORMULATIONS FOR AN ACCOMMODATING CONTACT LENS | Verily Life Sciences LLC (US) | 2019-07-31 | — | — | EP | disclosed |
| US-20180088352-A1 | CAST-MOLDABLE, HIGH REFRACTIVE INDEX, RIGID, GAS PERMEABLE POLYMER FORMULATIONS FOR AN ACCOMMODATING CONTACT LENS | VERILY LIFE SCIENCES LLC | 2018-03-29 | — | — | US | disclosed |
| US-9789655-B1 | Methods for mold release of body-mountable devices including microelectronics | VERILY LIFE SCIENCES LLC (US) | 2017-10-17 | — | — | US | disclosed |
| US-8815930-B2 | Compounds that inhibit TRPV1 and uses thereof | ABBVIE INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8748627-B2 | Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome | ABBVIE INC. (US) | 2014-06-10 | — | — | US | disclosed |
| WO-2004111009-A1 | FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2004-12-23 | — | — | WO | disclosed |
| US-20040254188-A1 | Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBVIE INC. | 2004-12-16 | — | — | US | disclosed |
| EP-1478363-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | Abbott Laboratories (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040209884-A1 | Fused azabicycic compounds that inhibit vanilloid receptor subtype 1(VR1) receptor | ABBVIE INC. | 2004-10-21 | — | — | US | disclosed |
| US-20040157849-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBVIE INC. | 2004-08-12 | — | — | US | disclosed |
| US-6693136-B1 | DISULFONAMIDE DERIVATIVES; PAIN, URINARY INCONTINENCE, BLADDER OVERACTIVITY | ABBOTT LABORATORIES | 2004-02-17 | — | — | US | disclosed |
| US-20040019042-A1 | FLUORENES AND ANTHRACENES THAT INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | ABBVIE INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003070247-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030158198-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBVIE INC. | 2003-08-21 | — | — | US | disclosed |
| US-20030158188-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBOTT LABORATORIES | 2003-08-21 | — | — | US | disclosed |