SCHEMBL8309467

SCHEMBL8309467

COC(=S)c1ccc(F)c(O)c1C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
ALDH1A1 P00352 1/20 0.35
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6584600 0.81 ALDH1A1 (0.34) ALDH1A1HSD17B10
SCHEMBL8310541 0.79 ALB (0.35) GAAALDH1A1
SCHEMBL20046459 0.78 ABL1 (0.46) GAAALDH1A1HSD17B10LMNA
SCHEMBL27323933 0.76 ALDH1A1 (0.46) GAAALDH1A1KMT2A
SCHEMBL8310539 0.73 ALB (0.38) ALDH1A1KMT2AMEN1HSD17B10
SCHEMBL27721513 0.72 CPS1 (0.38) GAAALDH1A1KMT2AMEN1
SCHEMBL8309433 0.72
SCHEMBL546258 0.70 ERN1 (0.39) ALDH1A1
SCHEMBL8310473 0.69 ALDH1A1 (0.33) GAAALDH1A1
SCHEMBL27494626 0.68 TUBB1 (0.41) GAAALDH1A1KMT2AMEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918056-A1 Herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1999-05-26 EP disclosed
WO-1999003856-A1 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-01-28 WO disclosed