Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 12/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358769 | 0.90 | MEN1 (0.56) | MEN1KMT2AKDM4EGSK3BUSP30 | |
| SCHEMBL7356227 | 0.86 | MEN1 (0.53) | MEN1KMT2AKDM4EGSK3BUSP30 | |
| SCHEMBL7355198 | 0.83 | MEN1 (0.55) | MEN1KMT2AUSP30CYP1A2CYP3A4 | |
| SCHEMBL8305264 | 0.81 | PSMB5 (0.47) | MEN1KMT2APSMB5 | |
| SCHEMBL9569135 | 0.81 | MEN1 (0.67) | MEN1KMT2AUSP30NPC1CYP1A2 | |
| SCHEMBL7361179 | 0.79 | MME (0.53) | — | |
| SCHEMBL7353133 | 0.78 | FCER2 (0.57) | PSMB5 | |
| SCHEMBL17913121 | 0.78 | MEN1 (0.66) | MEN1KMT2AKDM4EGSK3BUSP30 | |
| SCHEMBL7358942 | 0.77 | KMT2A (0.53) | MEN1KMT2APSMB5 | |
| SCHEMBL7353158 | 0.76 | FCER2 (0.57) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |