Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 10/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163619 | 0.91 | VCAM1 (0.50) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL7699048 | 0.90 | VCAM1 (0.56) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9328109 | 0.89 | VCAM1 (0.57) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9489745 | 0.88 | VCAM1 (0.60) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9489568 | 0.88 | VCAM1 (0.60) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9489600 | 0.88 | VCAM1 (0.60) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9491761 | 0.88 | VCAM1 (0.60) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9497169 | 0.87 | HPN (0.50) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9347028 | 0.85 | VCAM1 (0.52) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL9550708 | 0.84 | HPN (0.47) | VCAM1HPNMAPTALOX15SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293900-B1 | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase | SEARLE & CO (US) | 1994-03-16 | — | — | EP | claimed |
| EP-0293900-A2 | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase | G.D. Searle & Co. (US) | 1988-12-07 | — | — | EP | claimed |
| EP-3203540-A1 | ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE | FUJIFILM Corporation (JP) | 2017-08-09 | — | — | EP | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0293900-B1 | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase | SEARLE & CO (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5091569-A | Enzyme inhibitors; anti-oxidants to lipids; arteriosclerosis, antiallergens, antiulcer and antiinflammatory agents | SHIONOGI & CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| US-5002967-A | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase | G. D. SEARLE & CO. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0293900-A2 | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase | G.D. Searle & Co. (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4690995-A | Copolymers containing high concentrations of phenol antioxidant units | THE DOW CHEMICAL COMPANY (US) | 1987-09-01 | — | — | US | disclosed |