Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502537 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1S100A4FBP1 | |
| SCHEMBL6192325 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPK1TSHRNPBWR1 | |
| SCHEMBL27782191 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1NPBWR1FBP1 | |
| SCHEMBL6192327 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1TSHRNPBWR1 | |
| SCHEMBL9369721 | 0.71 | FASN (0.39) | ALDH1A1TDP1MAPK1TSHRKIF18A | |
| SCHEMBL9342102 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1TSHRKIF18A | |
| SCHEMBL11020276 | 0.71 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRNPBWR1GSK3B | |
| SCHEMBL11206355 | 0.71 | TDP1 (0.50) | ALDH1A1TDP1MAPK1TSHRS100A4 | |
| SCHEMBL6232168 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TDP1MAPK1TSHRKIF18A | |
| SCHEMBL10904423 | 0.70 | VCAM1 (0.42) | FBP1VCAM1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |