Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238467 | 0.88 | DPP4 (0.44) | DPP4DPP8MAPTHTTRIPK1 | |
| SCHEMBL27846788 | 0.84 | DPP4 (0.56) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL3719922 | 0.83 | DPP4 (0.48) | DPP4MAPTHTTALDH1A1DPP7 | |
| SCHEMBL3721167 | 0.83 | DPP4 (0.48) | DPP4MAPTHTTALDH1A1DPP7 | |
| SCHEMBL902826 | 0.83 | DPP4 (0.48) | DPP4MAPTHTTALDH1A1DPP7 | |
| SCHEMBL6692860 | 0.81 | DPP4 (0.43) | DPP4DPP8RIPK1DPP7DPP9 | |
| SCHEMBL8063678 | 0.78 | MAPK8 (0.46) | MAPTHTTRIPK1ALDH1A1MEN1 | |
| SCHEMBL22636115 | 0.75 | DPP4 (0.48) | DPP4DPP8ALDH1A1DPP7DPP9 | |
| SCHEMBL22636113 | 0.75 | DPP4 (0.48) | DPP4DPP8ALDH1A1DPP7DPP9 | |
| SCHEMBL6205091 | 0.74 | DPP4 (0.44) | DPP4DPP8RIPK1DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087650-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BETA-AMINO ACID AMIDE DIPEPTIDYL PEPTIDASE-IV INHIBITORS | MERCK & CO. INC. (US) | 2004-10-14 | — | — | WO | disclosed |