Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310272 | 0.95 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8306012 | 0.88 | TBXAS1 (0.79) | TBXAS1TBXA2R | |
| SCHEMBL8307227 | 0.87 | TBXAS1 (0.89) | TBXAS1TBXA2R | |
| SCHEMBL8308578 | 0.87 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8309158 | 0.86 | TBXAS1 (0.77) | TBXAS1TBXA2R | |
| SCHEMBL8305660 | 0.86 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8307025 | 0.84 | TBXAS1 (0.75) | TBXAS1TBXA2R | |
| SCHEMBL8307207 | 0.83 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8306671 | 0.83 | TBXAS1 (0.79) | TBXAS1TBXA2R | |
| SCHEMBL9710028 | 0.82 | TBXAS1 (0.78) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |