Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306769 | 0.90 | TBXAS1 (0.63) | TBXAS1ALDH1A1MEN1LMNAHTT | |
| SCHEMBL8310272 | 0.89 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8593388 | 0.89 | TBXAS1 (0.58) | TBXAS1TBXA2RALDH1A1LMNA | |
| SCHEMBL8306419 | 0.86 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8308715 | 0.85 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| SCHEMBL10461981 | 0.84 | TBXA2R (0.62) | TBXAS1TBXA2RALDH1A1MEN1LMNA | |
| SCHEMBL8310499 | 0.84 | TBXAS1 (0.69) | TBXAS1TBXA2R | |
| SCHEMBL8308709 | 0.83 | TBXAS1 (0.77) | TBXAS1TBXA2R | |
| SCHEMBL8307474 | 0.82 | TBXAS1 (0.58) | TBXAS1ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL8306671 | 0.82 | TBXAS1 (0.79) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |