Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311513 | 0.78 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL28333384 | 0.77 | — | — | |
| SCHEMBL8313764 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL27414160 | 0.74 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL27810023 | 0.74 | CHRM2 (0.38) | TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28060573 | 0.72 | CHRM2 (0.37) | MEN1KMT2A | |
| SCHEMBL4717467 | 0.71 | ALDH1A1 (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL27832023 | 0.71 | ALDH1A1 (0.34) | TSHRMEN1KMT2A | |
| SCHEMBL24310949 | 0.70 | TSHR (0.47) | TSHRSLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL1176768 | 0.70 | TSHR (0.47) | TSHRSLC6A1GABRA5GABRB2SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946545-A1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027085-A1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-25 | — | — | WO | disclosed |