Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16287024 | 0.84 | STS (0.49) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL8266055 | 0.84 | GPR119 (0.57) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2793493 | 0.81 | GPR119 (0.57) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL652849 | 0.80 | HTT (0.57) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL4139902 | 0.80 | DNMT3A (0.56) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL5013239 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL616004 | 0.80 | STS (0.60) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL18156538 | 0.80 | GPR119 (0.53) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL7381166 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTHTTSTSGPR119 | |
| SCHEMBL2797701 | 0.78 | ALDH1A1 (0.52) | ALDH1A1NPC1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019176-A1 | SUBSTITUTED AMINO-AZA-CYCLOHEXANES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-03-03 | — | — | WO | disclosed |