Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 12/20 | 0.46 |
| ▸ | NOS2 | P35228 | 12/20 | 0.46 |
| ▸ | NOS3 | P29474 | 10/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8308928 | 0.98 | NOS1 (0.44) | NOS1NOS2NOS3 | |
| SCHEMBL31264948 | 0.89 | CYP2C19 (0.42) | NOS1NOS2NOS3CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL31264976 | 0.87 | NOS3 (0.44) | NOS1NOS2NOS3CYP2C19KMT2A | |
| SCHEMBL31585483 | 0.82 | CHRM2 (0.33) | — | |
| SCHEMBL9373328 | 0.77 | NOS1 (0.47) | NOS1NOS2NOS3CYP2C19 | |
| Hydrochloric Acid SCHEMBL8306795 | 0.76 | NOS1 (0.45) | NOS1NOS2NOS3 | |
| SCHEMBL24664106 | 0.74 | POLB (0.33) | — | |
| SCHEMBL907524 | 0.74 | POLB (0.33) | — | |
| SCHEMBL433180 | 0.74 | POLB (0.33) | — | |
| SCHEMBL18733223 | 0.72 | NOS1 (0.43) | NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630244-B1 | MUSCARINIC AGONISTS | UNIV TOLEDO (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5403845-A | Cognition activators; Alzheimer*s disaease | UNIVERSITY OF TOLEDO (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0630244-A1 | MUSCARINIC AGONISTS | THE UNIVERSITY OF TOLEDO (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0630244-A4 | MUSCARINIC AGONISTS. | UNIV TOLEDO (US) | 1994-04-07 | — | — | EP | disclosed |
| WO-1993003726-A1 | MUSCARINIC AGONISTS | THE UNIVERSITY OF TOLEDO (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5175166-A | Cognition activators | THE UNIVERSITY OF TOLEDO (US) | 1992-12-29 | — | — | US | disclosed |