SCHEMBL8310779

SCHEMBL8310779

CNc1ccc2c(c1)CCCC2=O

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.67
MAOA P21397 4/20 0.56
MAOB P27338 4/20 0.56
PRKCI P41743 1/20 0.56
HSD17B1 P14061 2/20 0.50
CYP2A6 P11509 1/20 0.48
GRM5 P41594 1/20 0.47
MAPK14 Q16539 9/20 0.46
HIF1A Q16665 1/20 0.45
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15765661 0.89 CASP1 (0.53) BAZ2BMAOAMAOBPRKCIHSD17B1
SCHEMBL21505726 0.81 BAZ2B (0.74) BAZ2BMAOAMAOBPRKCIMAPK14
SCHEMBL315269 0.80 BAZ2B (1.00) BAZ2BMAOAMAOBPRKCIMAPK14
SCHEMBL30612414 0.80 BAZ2B (1.00) BAZ2BMAOAMAOBPRKCIMAPK14
SCHEMBL9715425 0.80 BAZ2B (0.60) BAZ2BMAOAMAOBPRKCIHSD17B1
SCHEMBL25124517 0.77 PARP10 (0.51) BAZ2BGRM5
SCHEMBL7837810 0.77 BAZ2B (0.73) BAZ2BMAOAMAOBPRKCIHSD17B1
SCHEMBL5120190 0.77 BAZ2B (0.94) BAZ2BMAOAMAPK14
SCHEMBL11732033 0.77 BAZ2B (0.56) BAZ2BMAOAMAOBPRKCIHSD17B1
SCHEMBL23657096 0.77 MAPK14 (0.69) BAZ2BGRM5MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230395857-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2023-12-07 US disclosed
US-11791499-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-10-17 US disclosed
US-11205802-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-12-21 US disclosed
EP-3758124-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2020-12-30 EP disclosed
US-20200036042-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2020-01-30 US disclosed
CN-110452686-A A kind of plasmosin assists enhanced class anthocyanidin fluorescent dye and preparation method thereof UNIV CHANGSHA SCIENCE & TECH 2019-11-15 CN disclosed
US-10476106-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-11-12 US disclosed
EP-2672561-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING SAME MITSUBISHI CHEM CORP (JP) 2019-04-17 EP disclosed
EP-2714675-B1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS INC (US) 2019-01-02 EP disclosed
EP-2714675-B1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS INC (US) 2019-01-02 EP disclosed
US-7566786-B2 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2009-07-28 US disclosed
US-7566786-B2 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2009-07-28 US disclosed
EP-1944305-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2008-07-16 EP disclosed
WO-2008051547-A1 FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS CEPHALON, INC. (US) 2008-05-02 WO disclosed
EP-1633748-B1 QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LTD (GB) 2008-03-05 EP disclosed
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2007-06-21 US disclosed
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2007-06-21 US disclosed
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors DEAN ANTHONY W 2007-03-01 US disclosed
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors DEAN ANTHONY W 2007-03-01 US disclosed
WO-2004103998-A1 QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors PDE3B, PDE4B, PDE4A BAZ2B 2473/4885MAOA 106/4885MAOB 87/4885
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors PDE3B, PDE4B, PDE4A BAZ2B 2473/4885MAOA 106/4885MAOB 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.