SCHEMBL8310796

SCHEMBL8310796

Cc1ccc(C=CC(=O)O)cc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.54
KDM4E B2RXH2 7/20 0.53
ALDH1A1 P00352 5/20 0.53
HSD17B10 Q99714 3/20 0.53
MAPK1 P28482 3/20 0.53
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA3 P07451 3/20 0.53
CA4 P22748 3/20 0.53
CA6 P23280 3/20 0.53
CA5A P35218 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CA5B Q9Y2D0 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
POLB P06746 3/20 0.53
HPGD P15428 2/20 0.53
AKR1B10 O60218 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8310794 1.00 NPSR1 (0.54) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL30423890 0.84 TUBB1 (0.46) NPSR1KDM4EALDH1A1TDP1POLB
SCHEMBL2908083 0.83 NPSR1 (0.59) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL584596 0.83 KDM4E (0.58) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL111230 0.83 KDM4E (0.58) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL2908080 0.83 NPSR1 (0.59) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL15950028 0.81 NPSR1 (0.53) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL15527953 0.80 NPSR1 (0.56) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL5859847 0.80 AKR1C3 (0.64) NPSR1KDM4EALDH1A1HSD17B10MAPK1
SCHEMBL9484682 0.80 KDM4E (0.70) NPSR1KDM4EALDH1A1HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746512-A Composition for forming cured film, alignment material, and phase difference material 日产化学株式会社 2022-07-12 CN disclosed
CN-106980233-B Cured film-forming composition, alignment material, and phase difference material 日产化学工业株式会社 2021-07-13 CN disclosed
CN-112384834-A Cured film, alignment material, and phase difference material 日产化学株式会社 2021-02-19 CN disclosed
CN-107463066-B Cured film-forming composition, alignment material, and phase difference material 日产化学工业株式会社 2020-10-30 CN disclosed
CN-105283512-B Composition for forming cured film, alignment material, and phase difference material 日产化学工业株式会社 2018-12-11 CN disclosed
CN-107463066-A Form the composition, orientation material and phase difference material of cured film 日产化学工业株式会社 2017-12-12 CN disclosed
US-9823400-B2 Cured film formation composition, orientation material, and retardation material NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-21 US disclosed
CN-103842447-B Cured film-forming composition, alignment material, and phase difference material 日产化学工业株式会社 2017-10-10 CN disclosed
CN-106980233-A Form the composition, orientation material and phase difference material of cured film 日产化学工业株式会社 2017-07-25 CN disclosed
CN-104603650-B It is orientated manufacture method, orientation material, the manufacture method of phase difference material and the phase difference material of material 日产化学工业株式会社 2017-06-06 CN disclosed
CN-104487510-A Cured film-forming composition, alignment material, and phase difference material NISSAN CHEMICAL IND LTD 2015-04-01 CN disclosed
CN-104204120-A Composition for forming cured film, orientation material, and phase difference material NISSAN CHEMICAL IND LTD 2014-12-10 CN disclosed
EP-2767562-A9 CURED FILM FORMATION COMPOSITION, ORIENTATION MATERIAL, AND PHASE DIFFERENCE MATERIAL Nissan Chemical Industries, Ltd. (JP) 2014-11-12 EP disclosed
US-20140239240-A1 CURED FILM FORMATION COMPOSITION, ORIENTATION MATERIAL, AND RETARDATION MATERIAL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-28 US disclosed
EP-2767562-A1 CURED FILM FORMATION COMPOSITION, ORIENTATION MATERIAL, AND PHASE DIFFERENCE MATERIAL Nissan Chemical Industries, Ltd. (JP) 2014-08-20 EP disclosed
CN-103842447-A Cured film-forming composition, alignment material, and phase difference material NISSAN CHEMICAL IND LTD 2014-06-04 CN disclosed
EP-0351856-B1 Thiazolo[5,4-b]azepine compounds TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-09-15 EP disclosed
US-5300639-A 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
US-5118806-A Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-06-02 US disclosed
US-4956360-A LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-11 US disclosed