Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316313 | 0.84 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL8311397 | 0.83 | PPARA (0.45) | PPARAPPARGACEPPARD | |
| SCHEMBL29908062 | 0.81 | PPARA (0.64) | PPARAPPARGACEPPARD | |
| SCHEMBL24570011 | 0.79 | PPARA (0.50) | PPARAPPARGACEPPARDMETAP2 | |
| SCHEMBL5217215 | 0.79 | ACE (0.62) | PPARAPPARGACEPPARD | |
| SCHEMBL8997911 | 0.79 | ACE (0.62) | PPARAPPARGACEPPARD | |
| SCHEMBL8997921 | 0.79 | ACE (0.62) | PPARAPPARGACEPPARD | |
| Trifluoroacetic Acid SCHEMBL8316396 | 0.75 | IDO1 (0.40) | PPARAPPARGPPARDMETAP2 | |
| SCHEMBL8314036 | 0.74 | PPARA (0.36) | PPARAPPARGACEPPARDMETAP2 | |
| SCHEMBL2238427 | 0.71 | METAP2 (0.53) | PPARAPPARGACEMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724601-A4 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORP (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0724601-A1 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995005398-A1 | S3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |