SCHEMBL2238427

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2235605	0.84	SMN1; SMN2 (0.45)	PPARGSMN1; SMN2NPC1RAB9APPID
	SCHEMBL2240346	0.83	ACE (0.57)	PPARAPPARGACE
	SCHEMBL11024016	0.82	METAP2 (0.57)	METAP2ELANEPPARAPPARGACE
	SCHEMBL11024021	0.82	METAP2 (0.57)	METAP2ELANEPPARAPPARGACE
	SCHEMBL11024018	0.82	METAP2 (0.57)	METAP2ELANEPPARAPPARGACE
	SCHEMBL1931193	0.81	MMP8 (0.56)	ELANEPPARGSMN1; SMN2PPIDMMP8
	SCHEMBL4560664	0.81	PDCD1 (0.55)	PPARGSMN1; SMN2NPC1PPIDMMP8
	SCHEMBL30354719	0.81	PDCD1 (0.55)	PPARGSMN1; SMN2NPC1PPIDMMP8
	SCHEMBL13915549	0.81	MMP8 (0.56)	ELANEPPARGSMN1; SMN2PPIDMMP8
	SCHEMBL8458621	0.81	METAP2 (0.50)	METAP2ELANEPPARAPPARGACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.