Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315150 | 0.88 | KMT2A (0.41) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8313674 | 0.83 | KMT2A (0.41) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8310590 | 0.81 | KMT2A (0.40) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8311050 | 0.81 | KMT2A (0.40) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8315166 | 0.81 | PTGS2 (0.40) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8315527 | 0.81 | KMT2A (0.39) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8310844 | 0.80 | KMT2A (0.41) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL6280223 | 0.80 | ADORA2A (0.50) | KMT2AADORA2AADORA1ALDH1A1GPR119 | |
| SCHEMBL8314841 | 0.79 | BLM (0.34) | TGFBR1TRPV1 | |
| SCHEMBL8315159 | 0.78 | KMT2A (0.41) | KMT2AADORA2AADORA1ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955292-A1 | Herbicidal 2-(cycloalk(en)yloxy)-6-(hetero)aryloxy(thio)pyridines | American Cyanamid Company (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0955292-A1 | Herbicidal 2-(cycloalk(en)yloxy)-6-(hetero)aryloxy(thio)pyridines | American Cyanamid Company (US) | 1999-11-10 | — | — | EP | disclosed |