Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CLK1 | P49759 | 2/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.57 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508628 | 0.81 | FLT3 (0.76) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL29431747 | 0.81 | FLT3 (0.76) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL28795137 | 0.78 | FLT3 (1.00) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL31060304 | 0.78 | FLT3 (1.00) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL31474881 | 0.78 | LCK (0.72) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL28987439 | 0.78 | LCK (0.72) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL648526 | 0.77 | FLT3 (0.76) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL25687336 | 0.76 | FLT3 (0.62) | FLT3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30402838 | 0.76 | KDM4E (1.00) | FLT3KDM4EALDH1A1GLAGAA | |
| SCHEMBL9989803 | 0.76 | FLT3 (0.73) | FLT3KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |