Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315112 | 0.97 | F2RL3 (0.33) | FFAR4F2RL3CYP19A1NDUFS2CHRM2 | |
| SCHEMBL8313166 | 0.87 | MAPK1 (0.36) | F2RL3CYP19A1 | |
| SCHEMBL8315851 | 0.86 | NPC1 (0.39) | F2RL3CYP19A1ADRA2C | |
| SCHEMBL8315236 | 0.85 | F2RL3 (0.32) | F2RL3 | |
| Hydrochloric Acid SCHEMBL8315734 | 0.85 | CYP19A1 (0.37) | F2RL3CYP19A1 | |
| SCHEMBL8312101 | 0.85 | MAPT (0.38) | F2RL3CYP19A1 | |
| SCHEMBL8316352 | 0.84 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL8310707 | 0.84 | F2RL3 (0.31) | F2RL3 | |
| SCHEMBL8310428 | 0.84 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL8311970 | 0.84 | MAPT (0.43) | CYP19A1CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |