SCHEMBL8310707

SCHEMBL8310707

FC(F)(F)c1csc(-c2cc3cc(OCc4ccccc4Cc4nnn[nH]4)ccc3o2)n1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.31
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30
AR P10275 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8310428 0.92 F2RL3 (0.33) F2RL3
Water SCHEMBL8314845 0.91 F2RL3 (0.32) F2RL3
SCHEMBL8315851 0.87 NPC1 (0.39) F2RL3
SCHEMBL8313166 0.86 MAPK1 (0.36) F2RL3PPARDPPARA
SCHEMBL8315236 0.85 F2RL3 (0.32) F2RL3
SCHEMBL8316352 0.85 F2RL3 (0.33) F2RL3
SCHEMBL8311024 0.84 FFAR4 (0.34) F2RL3
Hydrochloric Acid SCHEMBL8315734 0.84 CYP19A1 (0.37) F2RL3
SCHEMBL8312101 0.84 MAPT (0.38) F2RL3
SCHEMBL8314569 0.83 AR (0.36) F2RL3PPARDPPARAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0528337-B1 New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1999-10-20 EP disclosed
EP-0528337-A1 New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-02-24 EP disclosed