SCHEMBL8315236

SCHEMBL8315236

CC(C)(C)Cc1csc(-c2cc3cc(OCc4ccccc4Cc4nnn[nH]4)ccc3o2)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.32
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8310428 0.89 F2RL3 (0.33) F2RL3
Water SCHEMBL8314845 0.88 F2RL3 (0.32) F2RL3
SCHEMBL8315851 0.88 NPC1 (0.39) F2RL3
SCHEMBL8314647 0.87 S1PR1 (0.35) F2RL3
SCHEMBL8311502 0.87 S1PR1 (0.34) F2RL3
SCHEMBL8309897 0.86 NPC1 (0.32) F2RL3HTT
SCHEMBL8310707 0.85 F2RL3 (0.31) F2RL3
SCHEMBL8316352 0.85 F2RL3 (0.33) F2RL3
SCHEMBL8311024 0.85 FFAR4 (0.34) F2RL3
SCHEMBL8313166 0.84 MAPK1 (0.36) F2RL3NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0528337-B1 New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1999-10-20 EP disclosed
EP-0528337-A1 New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-02-24 EP disclosed