Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656297 | 0.93 | PRKCA (0.42) | PRKCAELANEMEN1KMT2A | |
| SCHEMBL10417600 | 0.78 | PRKCA (0.42) | PRKCAELANEMEN1KMT2A | |
| SCHEMBL1170858 | 0.78 | PRKCA (0.42) | PRKCAELANEMEN1KMT2A | |
| SCHEMBL24034315 | 0.74 | PRKCA (0.39) | PRKCAELANE | |
| SCHEMBL8990745 | 0.74 | PRKCA (0.39) | PRKCAELANE | |
| SCHEMBL31112926 | 0.74 | PRKCA (0.39) | PRKCAELANE | |
| SCHEMBL8310484 | 0.73 | PRKCA (0.38) | PRKCA | |
| Chloroform SCHEMBL8309854 | 0.72 | — | — | |
| SCHEMBL2478389 | 0.72 | TSHR (0.48) | PRKCAELANEMEN1KMT2A | |
| SCHEMBL8211801 | 0.72 | PRKCA (0.45) | PRKCAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |