Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309131 | 0.79 | LMNA (0.34) | LMNA | |
| SCHEMBL2656297 | 0.73 | PRKCA (0.42) | PRKCA | |
| Chloroform SCHEMBL8311136 | 0.73 | PRKCA (0.38) | PRKCA | |
| SCHEMBL8311628 | 0.73 | CYP2C19 (0.33) | LMNACYP2C19 | |
| SCHEMBL8427091 | 0.72 | PRKCA (0.43) | PRKCA | |
| SCHEMBL8307759 | 0.72 | LMNA (0.35) | LMNA | |
| SCHEMBL8311142 | 0.72 | PRKCA (0.39) | PRKCA | |
| SCHEMBL31112926 | 0.70 | PRKCA (0.39) | PRKCA | |
| SCHEMBL15743145 | 0.69 | PRKCA (0.46) | PRKCA | |
| SCHEMBL1170858 | 0.69 | PRKCA (0.42) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |