Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311067 | 0.96 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8310360 | 0.91 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8312666 | 0.91 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8314233 | 0.88 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8310523 | 0.85 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8314610 | 0.84 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8310464 | 0.84 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8310409 | 0.83 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8DRD4 | |
| SCHEMBL8310653 | 0.82 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8311394 | 0.80 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626954-B1 | BENZOCYCLOHEPTENES, BENZOXEPINES AND BENZOTHIEPINES | MERCK PATENT GMBH (DE) | 1999-03-17 | — | — | EP | claimed |