Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313110 | 0.83 | ESR1 (0.44) | ESR1ESR2APPALDH1A1LMNA | |
| SCHEMBL27480747 | 0.82 | ESR1 (0.43) | ESR1ESR2APPALDH1A1LMNA | |
| SCHEMBL8315658 | 0.81 | ALOX15 (0.43) | ESR1ESR2APPALDH1A1TDP1 | |
| SCHEMBL8310416 | 0.80 | ESR1 (0.42) | ESR1ESR2APPALDH1A1LMNA | |
| SCHEMBL8316603 | 0.80 | ALOX15 (0.42) | ESR1ESR2APPALDH1A1TDP1 | |
| SCHEMBL8310912 | 0.79 | MIF (0.54) | ESR1ESR2APPALDH1A1RAB9A | |
| SCHEMBL8311480 | 0.77 | ESR1 (0.47) | ESR1ESR2APPRAB9AMAPT | |
| SCHEMBL8314204 | 0.76 | KDM4E (0.39) | ESR1ESR2APPALDH1A1LMNA | |
| SCHEMBL8311144 | 0.76 | ESR1 (0.48) | ESR1ESR2APPALDH1A1LMNA | |
| SCHEMBL6600736 | 0.76 | ESR1 (0.48) | ESR1ESR2APPALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| CN-1036589-C | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-12-03 | — | — | CN | disclosed |
| CN-1033088-C | Thiazolylbenzofuran derivatives, processes for preparation thereof and pharmaceutical composition comprising same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-23 | — | — | CN | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| CN-1074444-A | New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-07-21 | — | — | CN | disclosed |
| CN-1070910-A | New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-04-14 | — | — | CN | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |