Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647863 | 0.91 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8292193 | 0.82 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL29527405 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6095071 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL214284 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5647422 | 0.80 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL5694265 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL27648318 | 0.79 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL14460126 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5648151 | 0.78 | PTGS2 (0.70) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018563-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A PHOSPHODIESTERASE INHIBITOR FOR THE TREATMENT OF ISCHEMIC MEDIATED CENTRAL NERVOUS SYSTEM DISORDERS OR INJURY | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |