Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691423 | 0.94 | TDP1 (0.50) | MAPTALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL7686834 | 0.93 | ALDH1A1 (0.52) | MAPTALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL7690995 | 0.91 | MAPT (0.49) | MAPTALDH1A1ACLYGAA | |
| SCHEMBL7685927 | 0.90 | PRMT1 (0.49) | MAPTALDH1A1HTTNPSR1ACLY | |
| SCHEMBL7683180 | 0.89 | MAPT (0.47) | MAPTALDH1A1HTTACLYGAA | |
| SCHEMBL7689285 | 0.89 | MAPT (0.51) | MAPTALDH1A1HTTL3MBTL1ACLY | |
| SCHEMBL7686086 | 0.85 | KDM4E (0.57) | MAPTSMN1; SMN2POLB | |
| SCHEMBL7686867 | 0.84 | MAPT (0.46) | MAPTALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL7685938 | 0.84 | MAPT (0.46) | MAPTALDH1A1HTTNPSR1ACLY | |
| SCHEMBL7689574 | 0.83 | MAPT (0.47) | MAPTALDH1A1HTTACLYGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |