Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312622 | 0.84 | KMT2A (0.51) | CYP19A1VCPKDM4EMAPTALDH1A1 | |
| SCHEMBL8310447 | 0.82 | CYP19A1 (0.50) | CYP19A1KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL8314667 | 0.79 | MEN1 (0.52) | CYP19A1VCPKDM4EMAPTALDH1A1 | |
| SCHEMBL8315476 | 0.78 | CYP19A1 (0.43) | CYP19A1KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL8314218 | 0.76 | CYP19A1 (0.41) | CYP19A1KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL8310912 | 0.75 | MIF (0.54) | KDM4EMAPTALDH1A1RAB9AHSD17B10 | |
| SCHEMBL8311831 | 0.74 | MAPT (0.63) | CYP19A1VCPKDM4EMAPTALDH1A1 | |
| SCHEMBL8311480 | 0.73 | ESR1 (0.47) | CYP19A1MAPTRAB9APDE4DMIF | |
| SCHEMBL8311144 | 0.72 | ESR1 (0.48) | KDM4EALDH1A1HSD17B10PDE4DSMN1; SMN2 | |
| SCHEMBL8312572 | 0.72 | ESR1 (0.48) | KDM4EALDH1A1HSD17B10PDE4DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| CN-1036589-C | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-12-03 | — | — | CN | disclosed |
| CN-1033088-C | Thiazolylbenzofuran derivatives, processes for preparation thereof and pharmaceutical composition comprising same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-23 | — | — | CN | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |