Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311847 | 0.89 | KMT2A (0.39) | CYP19A1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8315476 | 0.88 | CYP19A1 (0.43) | CYP19A1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL8314824 | 0.86 | MAPT (0.42) | CYP19A1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL8312884 | 0.86 | MAPT (0.47) | CYP19A1KDM4EALDH1A1MAPTCYP1A1 | |
| SCHEMBL8310220 | 0.85 | KDM4E (0.43) | CYP19A1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8311876 | 0.84 | FFAR4 (0.37) | CYP19A1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8311729 | 0.83 | F2RL3 (0.35) | CYP19A1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8310631 | 0.83 | F2RL3 (0.35) | CYP19A1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8310491 | 0.83 | F2RL3 (0.33) | CYP19A1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL8313181 | 0.82 | F2RL3 (0.35) | CYP19A1KDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |