SCHEMBL8311620

SCHEMBL8311620

CC(C)CN(C)c1ccc(C(=O)c2ccccc2C(=O)O)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
ALDH1A1 P00352 2/20 0.59
KDM4E B2RXH2 1/20 0.59
POLB P06746 1/20 0.59
GAA P10253 1/20 0.59
MCL1 Q07820 14/20 0.51
BCL2L1 Q07817 7/20 0.51
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010025 0.86 KMT2A (0.63) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9618590 0.85 KMT2A (0.78) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL10722949 0.85 KMT2A (0.81) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL11083430 0.84 ALDH1A1 (0.72) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9629674 0.83 ALDH1A1 (0.71) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9010008 0.83 KMT2A (0.65) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL10913804 0.82 KMT2A (0.62) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL29570529 0.82 KMT2A (0.72) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL6205557 0.82 KMT2A (0.72) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9320570 0.81 ALDH1A1 (0.83) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4101886-A None JP disclosed
EP-0462480-B1 Heat sensitive recording material and preparation process of said material MITSUI CHEMICALS INC (JP) 1999-03-24 EP disclosed
US-5300661-A Crystallizing the fluorene dyes in aqueous solvent solution MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-05 US disclosed
US-5283222-A Storage stable heat and pressure sensitive materials MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
US-5185453-A CRYSTAL OF FLUORAN COMPOUND MITSUI TOATSU CHEMICALS, INC. (JP) 1993-02-09 US disclosed
JP-H04101886-A THERMAL RECORDING MATERIAL MITSUI TOATSU CHEM INC 1992-04-03 JP disclosed
EP-0462480-A1 Crystal of fluoran compound, preparation process of said crystal, and recording material comprising said crystal MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-27 EP disclosed