Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308694 | 0.85 | ESR1 (0.47) | NR3C1LMNA | |
| SCHEMBL8311775 | 0.79 | GPR119 (0.51) | GPR119STSHRH3 | |
| SCHEMBL8309266 | 0.78 | F10 (0.57) | F10 | |
| SCHEMBL8311269 | 0.77 | F10 (0.59) | F10 | |
| SCHEMBL8311658 | 0.75 | F10 (0.58) | F10 | |
| SCHEMBL8449479 | 0.73 | F10 (0.62) | NR3C1F10LMNA | |
| SCHEMBL6951059 | 0.73 | GPR119 (0.53) | GPR119BMP1NR3C1RORCF10 | |
| SCHEMBL8309513 | 0.71 | F10 (0.48) | F10 | |
| SCHEMBL7561150 | 0.71 | F10 (0.47) | F10 | |
| SCHEMBL31681035 | 0.71 | GPR119 (0.60) | GPR119STSBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937723-A1 | Novel sulfonamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |