Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.45 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311642 | 0.79 | GPR119 (0.46) | GPR119STSHRH3 | |
| SCHEMBL9959434 | 0.76 | NLRP3 (0.51) | KCNA1KCNAB1 | |
| SCHEMBL6365439 | 0.75 | KCNA1 (0.60) | TGFBR1STSNPC1RAB9AKCNA1 | |
| SCHEMBL5778881 | 0.74 | KCNA1 (0.57) | TGFBR1NPC1RAB9ALIMK2KCNA1 | |
| SCHEMBL5440052 | 0.74 | KCNA1 (0.56) | TGFBR1STSNPC1RAB9ALIMK2 | |
| Hydrochloric Acid SCHEMBL8312274 | 0.74 | F10 (0.61) | — | |
| SCHEMBL8311347 | 0.73 | F10 (0.64) | — | |
| SCHEMBL5434427 | 0.73 | KCNA1 (0.55) | TGFBR1NPC1RAB9ALIMK2KCNA1 | |
| SCHEMBL9958499 | 0.72 | NAMPT (0.47) | TGFBR1KCNA1KCNAB1 | |
| SCHEMBL8590787 | 0.72 | F10 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937723-A1 | Novel sulfonamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |